An electronic bandage that can be attached directly to organs has been created
Since using pills or other medications can cause unwanted side effects by spreading the drug throughout the body, researchers are looking for ways to deliver the drug precisely to the area of interest. Researchers at Peking University have recently announced that they have developed a 'bandage that can be attached directly to organs.'
A battery-free nanofluidic intracellular delivery patch for internal organs | Nature
An electronic band-aid that delivers therapy directly to organs
The Third Hospital of Hokkaido University, Li Lu University, co-authored with Nature, published the results, showed the new type of transmission cost, NanoFLUID, selection of the tumor movement factor - Bioscience.
https://www.ebiotrade.com/newsf/2025-5/20250510074550390.htm
China makes paper-thin band-aid that sticks to organs, delivers drugs
https://interestingengineering.com/health/chinese-researchers-develop-organ-band-aid
There is a real need in the medical industry for a way to deliver medicine directly to organs, but traditional drug delivery systems pump vague packages of medicine into the body, requiring higher doses than necessary and potentially damaging organs along the way to their destination.
Furthermore, macromolecular drugs, or protein-based biopharmaceuticals, face an even greater challenge in that they are often inhibited by cell membranes, making it difficult for them to achieve the desired effect. Previous studies have shown that less than 2% of drugs injected intravenously reach the target tissue, with most drug molecules being captured by the mononuclear phagocyte system in the liver and spleen, or metabolized and removed by the kidneys.
NanoFLUID, a thin, electrically charged bandage developed by Mo Li and his colleagues at Peking University, creates tiny holes in cell membranes when attached to organs, making it easier to deliver drugs.
The bandage, which does not become a drug in itself but creates a 'path' for the drug to be delivered, has the advantage of being able to deliver the drug about 10 times faster, does not require electricity, and can directly interfere with the target area, Lee and his colleagues said.
Li and his colleagues are testing NanoFLUID in models of breast cancer, hepatitis, and developing tumors to verify its efficiency, safety, and controllability.
Tests have shown that the NanoFLUID has less than a 5% effect on cell viability and can be precisely controlled.
'NanoFLUID is an innovative platform for targeted drug delivery to internal organs. This research has already been applied to medical aesthetics and skin wound repair, and we are excited about its potential application to major health problems such as cancer,' said Lee and his colleagues.
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in Science, Posted by log1p_kr